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Dutasteride
is the generic name for a new dual 5 alpha-reductase inhibitor
made by GlaxoSmithKline. The drug is set to be marketed
under the name Avodart™ in the US and Avolve™
in Europe in December 2002.
The
FDA has approved Dutasteride for treating BPH (Benign
Prostate Hyperplasia), the same condition that Proscar™,
by made Merck, is used for. Dutasteride like Finasteride,
the active ingredient in Proscar and Propecia, also has
the added benefit of being able to be used to treat genetic
hair loss in men also known as MPB or Androgenic Alopecia.
The
difference between Dutasteride and Finasteride is that
Dutasteride inhibits the activities of both the type 1
and type 2 5AR enzymes unlike Finasteride which only inhibits
type 2. These enzymes are responsible for the conversion
of testosterone into DHT (dihydrotestosterone). DHT is
the primary cause of prostate growth and hair loss and
Dutasteride decreases levels of DHT by 90 percent after
only two weeks making it a much more powerful weapon against
hair loss and BPH.
Dutasteride.org
is a site dedicated to providing you with up-to date information
about the use of Dutasteride for BPH and Androgenic Alopecia.
It's important to note that the FDA has not approved Dutasteride
for the treatment of hair loss but Glaxo has completed
Phase 2 trials for its use in treating hair loss.
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HAIR LOSS RESOURCES
If
you are using Dutasteride or Avodart as a treatment
for thinning hair or hair loss
otherwise
known as
Male Pattern baldness, we recommend that
you
also
consult
these other resources
for more hair loss and hair transplant information.
Hairlosshelp.com -
General hair loss information resource for consumers
with a very active hair loss information forum.
Hairtransplant.net -
Site dedicated to surgical hair restoration and hair
transplant information with doctor profiles and articles
on hair transplantation.
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